Cognizin(Citicoline) – What Is It and Why You Need It!
Cognizin is a clinically recognized nootropic ingredient that supplies Citicoline to the human brain when given.
Citicoline is a brain-energizer that has been linked in human research to various cognition-enhancing and neuro-regenerative effects, including support for focus, recall, attention, and overall brain health. It is easily one of the best nootropics available, which is why it is a vital ingredient of GLYTCH Energy.
What Is Citicoline?
Citicoline (also known as cytidine-5-diphosphocholine or CDP-choline) is a substance found naturally in the human brain. It is a mixture of two substances: cytidine and choline. These substances have been linked to improved cognitive function and brain health; more on this later!
There is a distinction to be made between Citicoline and CDP-Choline. When physicians administer the compound as a therapy (for example, to aid brain injury recovery), it is referred to as Citicoline. It is CDP-Choline when it is produced naturally in the brain. However, the two compounds are identical.
Citicoline belongs to the cholinergic class of compounds, which refers to compounds that provide choline to the brain. Cholinergic are more complex molecules than straight choline, with a significantly higher bioavailability and ability to cross the blood-brain barrier.
Citicoline is the most bioavailable and potent cholinergic used in nootropics today. It provides more choline than Alpha-GPC, for example, while also providing more of the peripheral benefits associated with cytidine supplementation.
So, what exactly are the benefits of GLYTCH Energy Citicoline supplementation?
Benefits of Citicoline
1. Cognitive Improvement
Cognition tends to deteriorate with age due to decreased brain blood flow or other factors. According to a meta-analysis of 14 clinical trials, CDP-choline may improve memory and behavior in people with mild to moderate cognitive impairment, including those with poor brain circulation.
According to research data from over 2,800 elderly patients, citicoline treatment eliminated memory problems in 21% of cases. It improved them in 45% of cases.
Citicoline (1,000 mg daily for 9 months) helped 350 elderly patients with mild cognitive impairment because it:
- Strengthened nerve membranes
- Increased noradrenaline and dopamine levels
- Prevented oxidative damage
CDP-choline improves memory, reaction time, and behavior in three studies involving 210 patients with dementia and poor brain circulation. A higher dose of citicoline (2,000 mg) produced better results.
GLYTCH Energy Cognizin Nootropic Effects
- Energizes brain cells for peak cognitive performance while avoiding the crash caused by stimulants.
- Improves concentration, attention, information processing, and recall.
- Helps to maintain overall brain health and cognitive function.
- May help with mild age-related memory issues.
2. Stroke Rehabilitation
A cut in blood supply to a specific brain region can kill neurons and cause severe brain damage. Cognizin(Citicoline) could help by strengthening nerve membranes and inhibiting the production of free radicals.
According to a meta-analysis of four clinical trials (1,300+ patients), taking 2,000 mg of citicoline within the first 24 hours after a stroke increases the chance of complete recovery by 38%.
Citicoline improves outcomes and aids recovery; data from over 4,000 stroke survivors showed higher doses (2,000 – 4,000 mg) were more effective for recovery.
CDP-choline however had no significant benefits for acute stroke in two studies involving over 3,000 patients. Drugs that dissolve blood clots are still the first line of treatment for acute stroke. Citicoline is only proven to help stroke survivors recover, it cannot be used to treat acute stroke. It is important to note this
3. Vision Issues
Citicoline may have the same protective effects on the optic nerve as it does on the brain and spinal cord nerves. It may help with eye disorders such as Optic neuropathy, Glaucoma, and “Lazy eye” by reversing neuron damage in your retina.
4. Brain Damage
Environmental toxins, oxidative stress, and autoimmune responses can cause severe brain cell damage. Citicoline protects the brain and spinal cord from these stressors by preserving the myelin sheath of the cells and increasing vital neurotransmitters.
How Citicoline Works For Mental Performance and Brain Health
1. Brain Power
Cognizin(Citicoline) supports the proper function of mitochondria, which are the powerhouses that generate cellular energy. Higher levels of ATP energy in brain cells result from a healthy mitochondrial function, which powers the demanding tasks of higher-order cognition and brain regeneration.
2. Regeneration of the Brain
Citicoline, a cholinergic compound that increases phosphatidylcholine levels in the brain, promotes the formation and healthy function of brain cell membranes and energizes brain regeneration. Phosphatidylcholine is a phospholipid building block compound that accounts for approximately 30% of all brain tissue.
Citicoline has been shown to stimulate phospholipid synthesis and turnover, indicating brain renewal.
Citicoline aids in the formation of acetylcholine, the brain’s most important executive neurotransmitter. Acetylcholine is essential for working memory, learning, information processing, muscle contraction, and speech.
Citicoline may be a useful therapy for age-related cognitive decline because acetylcholine levels decline with age, and low acetylcholine is linked to brain degeneration, according to researchers. It may also promote the production of dopamine and norepinephrine, which are linked to more immediate benefits for mood and performance-driven cognition.
4. Circulation in the Brain
Citicoline has been proposed as a supplement to promote healthy cerebral circulation. In one study of patients with brain degeneration and memory problems, citicoline supplementation improved left temporal cerebral blood flow.
5. Protection of the Brain
Citicoline, like other brain-protective nootropic supplements, contains antioxidant activity that aids in neutralizing toxic free radicals with damaging effects on brain cells.
It provides an additional level of neuroprotective activity that may be even more important: it stimulates phosphatidylcholine synthesis, which helps to strengthen brain cell membranes and improve neural repair.
How Much Citicoline Dosage Should You Take?
1. How Much Citicoline Should You Take On A Daily Basis?
The dose of Citicoline you use ultimately depends on what you hope to gain from the nootropic. In humans, the usual daily therapeutic dose of citicoline is 500–2,000 mg for severe cases of cognitive decline, brain injury, or other medical conditions. In other words, a person of average body weight requires 7–28 mg/kg of Citicoline per day (70 kg).
However, you don’t need anywhere near this much Citicoline for day-to-day cognitive enhancement. According to clinical evidence, as little as 150mg of Citicoline per day can significantly improve focus, learning, and information processing speeds.
Up to about 250mg per day, there is a dose-dependent relationship. Beyond that, higher doses of Citicoline do not appear to provide any additional benefits to otherwise healthy people.
Can You Take Cognizin(Citicoline) On A Daily Basis?
1. Is It Safe To Take Citicoline On A Daily Basis?
It is not only safe to take Citicoline on a daily basis, but it is also recommended. Citicoline is far more beneficial when taken daily than when taken infrequently.
Citicoline works through a variety of mechanisms. One of these is increased brain cell maintenance and development through cytidine donation. Supplementing with citicoline promotes more efficient brain cell development and maintenance. Long-term, daily Citicoline use has been shown to have significant advantages over infrequent use due to improved brain cell development and health.
Citicoline also significantly improves mitochondrial function in brain cells. Taking it as a one-time nootropic supplement has little impact on your cognitive function. On the other hand, when used daily produces a significant, noticeable, and almost permanent increase in brain energy levels.
Citicoline (CDP-choline) protects nerves by strengthening their membranes and increasing levels of essential neurotransmitters. It also has nootropic effects in healthy people, prevent cognitive decline in the elderly, and aid in stroke recovery.
Citicoline is a safe and well-tolerated medication. Mild side effects such as headaches and stomach upset are possible. Pregnant women, children, and people allergic to choline-containing supplements should avoid it, while others should first consult their doctor.
If you’re looking for natural and targeted ways to improve your brain power, GLYTCH Energy is the best bet for you!